Biologics, Module 8
The backyard
Picture kids camping in the backyard — tents up, everything calm. cAMP = the CAMP. PDE4 normally breaks down cAMP (tears down the tents). Apremilast blocks PDE4 — the kids keep camping, everything stays calm.
“Block PDE, let cAMP stay — APREMILAST saves the day.”
Apremilast (Otezla) — Oral
Mechanism: PDE4 inhibitor. Oral. Raises intracellular cAMP → reduce…
