IL-1 is the front door — the first signal that kicks off autoinflammatory fires (gout, FMF, CAPS, Still’s disease). These drugs guard the door.
α = IL-1 alpha · β = IL-1 beta · Wall = IL-1 Receptor
“ANA catches ALL at the wall. CANA lets alpha crawl in. RILO snaps the trap — -cept gets ‘em all.”
Anakinra (Kineret) — SC
Mechanism: IL-1 receptor antagonist (r…



